Group leaders
Sean Clouston
Stony Brook Medicine, New York, USA

Cécile Proust-Lima
ISPED, Bordeaux, France
The specification of the time-scale(s) and functions of within-person change in longitudinal studies can dramatically influence results and replicability. Because of the close link between age and dementia, age constitutes a natural and appropriate time-scale for studying dementia risk and its determinants. In studies of cognitive decline, other metrics of time are however sometimes relevant (e.g., time to diagnosis, time to death).